Searchable abstracts of presentations at key conferences in endocrinology

ea0029oc2.3 | Thyroid Clinical I | ICEECE2012

Thyroid hormone levels in euthyroid young men are associated with body composition and metabolic parameters

Roef G. , Taes Y. , Lapauw B. , Wierckx K. , Kaufman J.

Introduction: Thyroid disorders affect metabolism and body composition; however, literature data have been conflicting on whether this is also the case for thyroid hormone levels within the euthyroid range. Therefore, we have investigated the relationship between indices of thyroid status and both body composition and metabolic parameters in a population of healthy euthyroid men.Methods: Healthy male siblings (n=941, 25–45 years, median BMI 2...

ea0029p405 | Clinical case reports - Thyroid/Others | ICEECE2012

Pubertal induction with testosterone of a boy with bilateral anorchia guided by the development of his monozygotic twin brother

Van Caenegem E. , Vandewalle S. , Wierckx K. , Taes Y. , Kaufman J. , Craen M. , T'Sjoen G.

Introduction: We describe a monozygotic twin pair, of which one boy was diagnosed with anorchia. Both were followed-up till age 17.Case report: At birth, in one twin 46 XY boy (A), testes were not palpable while his brother (B) was unaffected. Stimulation with human chorionic gonadotrophin (hCG) and orchidopexia were unsuccessful at age 3. A second hCG-stimulation test was performed at age 8, where serum testosterone response failed to increase. No testi...

ea0029p1559 | Steroid metabolism + action | ICEECE2012

Long-term evaluation of cross-sex hormone treatment in transsexual persons

Wierckx K. , Weyers S. , Caenegem E Van , Roef G. , Heylens G. , T'Sjoen G.

Objective: To describe the effects and side effects of cross-sex hormone therapy in both transsexual men and women.Design: Single center cross-sectional study in one hundred transsexual persons post SRS and on average 10 years on cross-sex hormone therapy.Methods: Hormone levels were measured by immunoassays. Physical health was assessed by physical examination and questionnaires on general health and specific side effects, areal b...

ea0026p164 | Neuroendocrinology | ECE2011

Sexual desire in female-to-male transsexual persons

Wierckx K , Van De Peer F , Dedecker D , Van Caenegem E , Elaut E , T'Sjoen G

Objective: The current study aims to describe sexual desire in female-to-male transsexuals post SRS (sex reassignment surgery) using a validated questionnaire. The association between serum androgen levels and the intensity and frequency of sexual desire are examined. The data are compared to those of male-to-female transsexual persons.Design: Cross sectional study.Methods: Female-to-male transsexual persons, post SRS, (n=48...

ea0026p355 | Steroid metabolism | ECE2011

Salivary cortisol and testosterone: a comparison of salivary sample collection methods in healthy controls

Van Caenegem E , Wierckx K , Fiers T , Segers H , Vandersypt E , Kaufman J M , T'Sjoen G

Context: In population and psychosocial studies, saliva becomes increasingly popular, mainly due to its non-invasive collection methods and availability of free hormone fractions. However, few studies have evaluated the impact of collection devices on steroid hormone analysis; and none with the currently used methods.Objective: The aim of this pilot study was to minimize pre-analytical errors based on sample collection methods.Meth...